Early double sequential defibrillation in out-of-hospital cardiac arrest
DoubleD-Trial is an academic, investigator-initiated, open-label randomised trial. The aim is to evaluate whether early double sequential defibrillation (DSD) improves survival compared to standard defibrillation in out-of-hospital cardiac arrest (OHCA). Patients with an initial shockable rhythm, who remain in cardiac arrest after at least one standard shock are screened for inclusion. The trial is coordinated by the Centre for Resuscitation Science, Karolinska Institutet (sponsor). For more information, see the pilot study and the main trial.

Welcome NU Hospital Group!
We are happy to announce that NU Hospital Group (NU-sjukvården, Trollhättan area, Sweden) in Västra Götaland Region are up and running with local PI Carl Magnusson and local study coordinators

🚑 New Site Activation – Södra Älvsborgs Sjukhus (SÄS), Borås, Sweden!
We are thrilled to announce that Södra Älvsborgs Sjukhus (SÄS) in Borås has officially joined the Double-D Trial family! As of today, the SÄS EMS team have begun enrolling patients,

Akil Awad presented Double-D at ERC 2025 in Rotterdam
At this year’s European Resuscitation Council (ERC) congress in Rotterdam, Akil Awad presented results from the Swedish study Double-D’s pilot phase during the Late Breaking / Hot Topic session. The
